TABLE 3.
Trends in the susceptibility of the five leading microorganisms in patients with community-onset bacteremia
| Microorganisma | Susceptibilityb (%) |
P valuec | |||
|---|---|---|---|---|---|
| Young adults (18–44 yr) | Adults (45–64 yr) | The elderly (65–84 yr) | Oldest old (≥85 yr) | ||
| Escherichia coli | n = 62 | n = 264 | n = 494 | n = 148 | |
| Cefazolin-S | 64.5 | 56.8 | 55.3 | 48.6 | 0.027 |
| Cefuroxime-S | 79.0 | 78.0 | 72.1 | 66.2 | 0.035 |
| Cefotaxime-S | 98.4 | 90.2 | 88.9 | 83.1 | 0.034 |
| Levofloxacin-S | 90.3 | 84.1 | 82.0 | 68.9 | 0.049 |
| ESBL producer | 3.2 | 4.5 | 5.9 | 9.5 | 0.035 |
| Klebsiella pneumoniae | n = 17 | n = 123 | n = 164 | n = 50 | |
| Cefazolin-S | 88.2 | 79.7 | 73.2 | 62.0 | 0.006 |
| Cefuroxime-S | 94.1 | 93.5 | 86.0 | 82.0 | 0.041 |
| Cefotaxime-S | 100 | 95.9 | 91.5 | 88.0 | 0.001 |
| Levofloxacin-S | 100 | 95.1 | 90.9 | 86.0 | <0.001 |
| ESBL producer | 0 | 4.1 | 5.5 | 12.0 | 0.031 |
| Staphylococcus aureus | n = 30 | n = 114 | n = 124 | n = 44 | |
| Methicillin-R | 6.9 | 31.6 | 37.9 | 59.1 | 0.021 |
| Streptococcus species | n = 27 | n = 90 | n = 125 | n = 47 | |
| Penicillin-S | 96.3 | 94.4 | 93.6 | 89.4 | 0.047 |
| Cefotaxime-S | 96.3 | 94.4 | 94.4 | 97.9 | 0.673 |
| Levofloxacin-S | 100 | 98.9 | 96.8 | 93.6 | 0.023 |
| Pseudomonas aeruginosa | n = 9 | n = 16 | n = 46 | n = 13 | |
| Ceftazidime-S | 77.8 | 100 | 100 | 84.6 | 0.765 |
| Cefepime-S | 77.8 | 100 | 100 | 84.6 | 0.765 |
| Levofloxacin-S | 88.9 | 87.5 | 91.3 | 84.6 | 0.542 |
a
S, susceptible.
b
n indicates the number of isolates in various age groups.
c
Calculated by Pearson's correlation. Boldface indicates statistical significance, i.e., a P value of <0.05.