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. 2017 Nov 22;61(12):e01535-17. doi: 10.1128/AAC.01535-17

TABLE 1.

Properties of the S. pneumoniae strains

Strain Sourcea Date Age (yr) Sex Site of isolationb Serotype or serogroup STc MICd (μg/ml)
 Susceptibilitye
 pbp2x GenBank accession no.
PEN OXA CTX AMX ERY TET CAM GEN SXT
IR13 Sina Hospital 2008 68 Male CSF 6A/B 81 S S S R S MF506856
IR52 Roghayyeh Nursery 2011 2 Male Nasopharynx 9V 558 S S R R R MF506857
IR120 Shobeir Nursery 2011 3 Male Nasopharynx 19A 13331 S S S R R MF506858
IR135 Shobeir Nursery 2011 2 Female Nasopharynx 4 NDf R R R R R MF506859
IR148 Ameneh Nursery 2011 2 Male Nasopharynx 3 13387 S S S R R MF506861
IR136 Ameneh Nursery 2011 3 Male Nasopharynx 4 13330 S S S R R MF506860
IR158 Roghayyeh Nursery 2011 2 Female Nasopharynx 6A/B 13329 S S S R R MF506862
IR164 Roghayyeh Nursery 2011 0.5 Male Nasopharynx 6A/B 13328 S S S R R MF506863
IR174 Roghayyeh Nursery 2011 1.5 Female Nasopharynx ND ND S S R R R MF506864
RO6 Victor Babes hospital 2004 55 Male PF 19 4–8 16 0.5 8 R R R MF506865
RO27 Coltea Hospital 2003 79 Female Sinus 19 4–8 32 0.5 8 R R S MF506866
RO31 Victor Babes Hospital 2004 19 Male TA 6 4–6 24 0.5 2 R R S MF506867
RO33 Victor Babes Hospital 2003 10 Male TA 4 24 0.5 8 R R S MF506868
RO34 Victor Babes Hospital 2004 51 Female PF 19 4–8 16 0.5 8 R R S MF506869
RO36 Marie Curie Hospital 2003 4 Male TA 1.5–4 12 0.5 2 R R S MF506870
RO56 Coltea Hospital 2004 61 Male Sputum 19 0.5–4 6 0.5 1 S R S MF506871
RO58 Victor Babes Hospital 2004 12 Female TA 19 3–4 16 0.5 4 R R S MF506872
RO61 Victor Babes Hospital 2004 46 Male TA 19 4 24 0.5 4 R R S MF506873
RO67 Coltea Hospital 2004 69 Male Sputum 19 2–4 8 1 2 S S R MF506874
RO76 Marie Curie Hospital 2004 3 Female Ear 19 8 48 8 >8 R S S MF506875
RO85 Victor Babes Hospital 2004 7 Female TA 3–8 24 0.5 2 R R S MF506876
RO94 Marie Curie Hospital 2004 2 Male TA 4–8 24 4 8 S S S MF506877
RO106 Marie Curie Hospital 2004 5 Male TA 19 4–8 16 0.5 8 R R S MF506878
RO116 Marie Curie Hospital 2003 1 Female CS 19 3–4 1.5–2 2 2 S S S MF506879
a

The hospitals or nurseries are located in Tehran (Iranian [IR] isolates) or Bucharest (Romanian [RO] isolates).

b

TA, tracheal aspirate; PF, pleural fluid; CS, conjunctival secretion; CSF, cerebrospinal fluid; Ear, middle ear fluid.

c

ST, sequence type defined by MLST; the pulsed-field gel electrophoresis (PFGE) pattern of strain IR174 was identical to that of strain IR148 (not shown).

d

MIC values for β-lactam antibiotics were determined by the agar dilution method; for all other antibiotics, the Kirby-Bauer disk diffusion test was used. All isolates from Iran were resistant to oxacillin and susceptible to cefotaxime, according to published guidelines (61). PEN, penicillin; OXA, oxacillin; CTX, cefotaxime; AMX, amoxicillin.

e

ERY, erythromycin; TET, tetracycline; CAM, chloramphenicol; GEN, gentamicin; SXT, trimethoprim-sulfamethoxazole; S, susceptible; R, resistant.

f

ND, not determined.