Table III.
Stratification analyses between murine double minute-2 T309G genotypes and gastric cancer risk.
| MDM2 T309G | Controls (n=67) | Gastric cancer (n=65) | χ2 | P-value | Crude odds ratio |
|---|---|---|---|---|---|
| Allele frequency | |||||
| T allele | 65 | 47 | Ref. | 0.042 | 1.66 (0.99–2.81) |
| G allele | 69 | 83 | 4.12 | ||
| Genotype frequency | |||||
| TT | 10 (14.9) | 4 (6.2) | Ref. | – | – |
| TG | 45 (67.2) | 39 (60.0) | 1.55 | 0.213a | 2.16 (0.62–7.45) |
| GG | 12 (7.9) | 22 (33.8) | 5.21 | 0.022 | 4.58 (1.18–17.79) |
| TG + GG | 57 (85.1) | 61 (93.8) | 2.67 | 0.102 | 2.65 (0.79–9.01) |
| TT + TG | 45 (67.2) | 39 (60.0) | 0.73 | 0.392 | 0.73 (0.36–1.49) |
a
Fisher's exact test. MDM2, murine double minute-2.