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Enforced expression of variant ATF7IP/PDGFRB fusion induced cytokine-independent growth and glucocorticoid resistance of BaF3 cells. (A) Compared with the parental BaF3 cells which can grow in the media with IL-3 (10 ng/mL), the cells stably transfected with variant ATF7IP/PDGFRB fusion became IL-3-independent growth. (B) The transformed BaF3 cells acquired resistance to dexamethasone treatment, even under a high concentration of the drug (10 μM).
