Table 3.
Causes of death among all individuals with intellectual disability and the matched control population
| Causes of death | Deaths among individuals with intellectual disability (ID) (n = 4738) | Deaths among matched control population (n = 8364) |
Adjusted cause-specific mortality rate ratio (95% CI)* | ||
|---|---|---|---|---|---|
| Number of deaths n (%) |
Cause-Specific Mortality Rate (per 100,000 people) | Number of deaths n (%) |
Cause-Specific Mortality Rate (per 100,000 people) | ||
| Ch. I – Certain infectious and parasitic diseases, A00-B99 | 181 (3.8) | 95 | 170 (2.0) | 16 | 5.32 (4.32–6.56) |
| Ch. II – Neoplasms, C00-D48 | 710 (15.0) | 372 | 2749 (32.9) | 266 | 1.29 (1.19–1.40) |
| Ch. III – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, D50-D89 | 25 (0.5) | 13 | 21 (0.3) | 2 | 5.95 (3.33–10.6) |
| Ch. IV – Endocrine, nutritional and metabolic diseases, E00-E90 | 174 (3.7) | 91 | 228 (2.7) | 22 | 3.82 (3.13–4.65) |
| Ch. V – Mental and behavioural disorders, F00-F99 | 224 (4.7) | 117 | 342 (4.1) | 33 | 3.27 (2.77–3.88) |
| Ch. VI – Diseases of the nervous system, G00-G99 | 296 (6.3) | 155 | 325 (3.9) | 31 | 4.55 (3.89–5.33) |
| Ch. IX – Diseases of the circulatory system, I00-I99 | 1601 (33.8) | 839 | 2959 (35.4) | 287 | 2.71 (2.55–2.87) |
| Ch. X – Diseases of the respiratory system, J00-J99 | 807 (17.0) | 423 | 530 (6.3) | 51 | 7.61 (6.82–8.49) |
| Ch. XI – Diseases of the digestive system, K00-K93 | 205 (4.3) | 107 | 318 (3.8) | 31 | 3.22 (2.70–3.84) |
| Ch. XII – Diseases of the skin and subcutaneous tissue, L00-L99 | 5 (0.1) | 3 | 14 (0.2) | 1 | 1.79 (0.64–4.96) |
| Ch. XIII – Diseases of the musculoskeletal system and connective tissue, M00-M99 | 30 (0.6) | 16 | 40 (0.5) | 4 | 3.75 (2.34–6.02) |
| Ch. XIV – Diseases of the genitourinary system, N00-N99 | 105 (2.2) | 55 | 99 (1.2) | 10 | 5.30 (4.03–6.98) |
| Ch. XVI - Certain conditions originating in the perinatal period, P00-P96 | 9 (0.2) | 5 | 0 (0) | 0 | NA |
| Ch. XVII – Congenital malformations, deformations and chromosomal abnormalities, Q00-Q99 | 49 (1.0) | 26 | 5 (0.1) | 0.5 | 49.0 (19.5–123) |
| Ch. XVIII – Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified, R00-R99 | 166 (3.5) | 87 | 208 (2.5) | 20 | 3.99 (3.25–4.89) |
| Ch. XIX – Injury, poisoning and certain other consequences of external causes, S00-T98 | 6 (0.1) | 3 | 0 (0) | 0 | NA |
| Ch. XX – External causes of morbidity and mortality, V01-Y98 | 144 (3.0) | 75 | 356 (4.3) | 34 | 2.02 (1.67–2.45) |
The control population was matched by sex, birth year and year of first hospitalisation/access to LSS services to individuals with ID. The total follow-up period for individuals with ID was 190,788 person-years, and for the control population was 1,032,245 person-years. The adjusted mortality rate ratio was obtained using conditional fixed-effects Poisson regression