Table 3.

Lower genital tract infection indicators in pregnant (ANC1) and non-pregnant (FIN) cohorts by trial arm

Assessment	Infection marker	N	Trial arm		Unadjusted		Adjusteda
			Iron (%)	Control (%)	RR (95% CI)	P valueb	Nc	RR (95% CI)	P valuec
Pregnant	Bacterial vaginosisd	298				0.776	245		0.704
ANC1	Nugent 7–10e	298	12/152 (7.9)	9/146 (6.2)	1.28 (0.56–2.95)	0.653	245	0.93 (0.33–2.56)	0.881
N = 315	Nugent 4–6e	298	17/152 (11.2)	19/146 (13.0)	0.86 (0.47–1.59)	0.723	245	0.94 (0.47–1.88)	0.858
	Nugent 0–3e	298	123/152 (80.9)	118/146 (80.8)	1.00 (0.90–1.12)	1	245	1.03 (0.91–1.15)	0.665
	T. vaginalis f	286	23/147 (15.6)	14/139 (10.1)	1.55 (0.83–2.90)	0.217	286	1.55 (0.83–2.90)	0.168
	Vaginal discharge	315	14/163 (8.6)	12/152 (7.9)	1.09 (0.52–2.28)	0.841	315	1.08 (0.51–2.25)	0.846
	pH ≥ 4.5	309	92/158 (58.2)	86/151 (57.0)	1.02 (0.84–1.24)	0.908	260	1.06 (0.86–1.31)	0.555
Non-pregnant	Bacterial vaginosisd	671				0.588	546		0.676
FINf	Nugent 7–10e	671	46/341 (13.5)	40/330 (12.1)	1.11 (0.75–1.65)	0.645	546	0.86 (0.56–1.34)	0.509
N = 877	Nugent 4–6e	671	35/341 (10.3)	26/330 (7.9)	1.30 (0.80–2.11)	0.347	546	1.21 (0.72–2.03)	0.467
	Nugent 0–3e	671	260/341 (76.2)	264/330 (80.0)	0.95 (0.88–1.03)	0.263	546	0.99 (0.90–1.08)	0.806
	T. vaginalis f	716	20/360 (5.6)	15/356 (4.2)	1.32 (0.69–2.53)	0.489	716	1.30 (0.67–2.50)	0.432
	Vaginal discharge	874	49/425 (11.5)	31/449 (6.9)	1.67 (1.09–2.57)	0.019	874	1.63 (1.06–2.51)	0.026

^aAdjusted for baseline infection and use of antibiotics in previous 3 months

^bFishers exact test

^cLogistic regression

^dEach group compared to both other groups

^eExcludes those less than 6 months post menarcheal

^fBaseline not available