Table 5.

Mean number of health centre antibiotic treatments in non-pregnant cohort by infection diagnosis and trial arm from enrolment to FIN

Infection indication	Iron	Control	Iron per 50 visits n = 26,473	Control per 50 visits n = 27,633	Incidence ratioa (95% CI)	P value	PFDRb
Malariac	41	28	0.077	0.051	1.53 (0.94–2.47)	0.084	0.278
Respiratory	75	87	0.142	0.157	0.90 (0.66–1.23)	0.503	0.719
Locald	75	57	0.142	0.103	1.37 (0.97–1.94)	0.071	0.278
Gastrointestinale	62	30	0.117	0.054	2.16 (1.39–3.34)	<0.001	0.005
Urinary tractf	10	9	0.019	0.016	1.16 (0.47–2.86)	0.747	0.934
STIg	13	7	0.025	0.013	1.94 (0.77–4.86)	0.158	0.292
Genitalh	15	16	0.028	0.029	0.98 (0.48–1.98)	0.952	0.993
Dental	11	5	0.021	0.009	2.30 (0.80–6.62)	0.123	0.292
Meningitis	0	3	0	0.005	0 (NA)	0.993	0.993
Miscellaneousi	29	42	0.055	0.076	0.72 (0.45–1.16)	0.175	0.292

^aIncidence ratio was computed using Poisson regression with the number of visits as the exposure period

^b P value adjusted for multiple testing using false discovery rate method [26]

^cAntibiotics in addition to anti-malarial treatment

^dNon-enteric and non-respiratory, includes ear, skin, ophthalmic, abscess, wounds, local trauma, sinusitis, mastoiditis, keloid, scalp ringworm

^eDysentry, typhoid, enteritis, intestinal parasitosis, gastric ulcer, gastroenteritis, diarrhoea and abdominal pain, vomiting and abdominal pain, amoebiasis, colopathy, sub-occlusion

^fCystitis, dysuria

^gIncludes syphilis, trichomoniasis

^hUpper or lower genital infection

ⁱItching, colic, headache, generalised or localised pain, fever, vomiting only, anaemia, anxiety, neuralgia, spasms, urticarial, plus non-infectious specific diagnoses: cancers, fertility problems, angina, self-medication, allergy, burns, renal stones, contraception, thyroid and cardiac diseases, epilepsy, filariasis, foreign body, venomous bites, fractures, migraine, HIV, varicella, mumps, prophylactic and non-classifiable: includes three uncertain descriptors, or absent statement

PFDR positive false discovery rate, STI sexually transmitted infection