Table 2.
Suspected elicitors of anaphylaxis in children/adolescents and adults fulfilling the WAO/EAACI criteria for the diagnosis of anaphylaxis (n = 180)
| Suspected elicitors | Children/adolescents n = 23 (%) |
Adults n = 157 (%) |
p value |
|---|---|---|---|
| Drugs | 5 (22) | 75 (48) | 0.019 |
| β-lactam antibiotic | 1 (20) | 30 (40) | |
| ACE inhibitors | 0 | 13 (17) | |
| ASA/NSAIDs | 3 (60) | 9 (12) | |
| Other drugsa | 1 (20) | 23 (31) | |
| Food | 14 (61) | 26 (17) | <0.001 |
| Tree nuts | 7 (50) | 8 (31) | |
| Peanuts | 3 (21) | 1 (4) | |
| Fish/shellfish | 0 | 3 (11) | |
| Wheat | 0 | 3 (11) | |
| Other foodsb | 4 (29) | 11 (42) | |
| Venom | 1 (4) | 37 (24) | 0.035 |
| Wasp | 1 (100) | 25 (67) | |
| Bee | 0 | 8 (22) | |
| Other insectsc | 0 | 4 (11) | |
| Inhalation allergens | 1 (4) | 1 (1) | 0.113 |
| Unknown | 2 (9) | 18 (11) | 0.693 |
a Iodinated Radio Contrast Media n = 5, Macrolides n = 1, Miconazole n = 1, Acyclovir n = 1, Chloramphenicol n = 1, Metronidazole n = 2, Proton pump inhibitor n = 1, Acrivastine n = 1, Chlorhexidine n = 1, Gabapentin n = 1, Camphorated opium tincture n = 1, Xylometazoline n = 1, Lamotrigine n = 1, topic Glucocorticoids n = 1, Calcium antagonist (felodipine) n = 1, Mesalazine n = 1, Valerian root n = 1, Zopiclone n = 1, D- vitamin n = 1
b Milk n = 1, Carrot n = 1, Celery n = 1, Bugles chips n = 1, Oatmeal breakfast cereal n = 1, Tomato n = 1, Fruit/fig bars (apple/raspberry) n = 1, Kiwi, parsley root and parsnip n = 1, Poppy seed n = 1, Carry n = 1 Chicken, bread, pasta, sour cream n = 1, Dressing (hydrolysate) n = 1, Red wine n = 1, Jensens Bøfhus® sauce n = 1, Noodle soup n = 1
c Bumblebee, gadfly
Boldface are marking the different groups of elicitors and for each group the percentage distribution of the specific elicitors are given