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. 2017 Nov 22;17:218. doi: 10.1186/s12866-017-1129-9

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Persister cells in exponential growth phase in presence of combined antibiotic treatment. The exponentially growing cells (USA300 LAC, msaABCR mutant and the complementation) were treated with combined antibiotics. a. daptomycin/rifampicin (40× MIC), b. vancomycin/rifampicin (20× MIC), c. linezolid/rifampicin (20× MIC), d. daptomycin/gentamicin (20× MIC), e. vancomycin/gentamicin (20× MIC), and f. linezolid/gentamicin (20× MIC). Student’s t-test (OriginPro) was used to compare the results of the wild-type to mutants at respective designated time points (* p-value <0.05, ** p-value <0.005). These results represent the means of three independent experiments. Error bars represent SE