Table 2.
The side effects of chemotherapy regimen of the combination of pemetrexed and nedaplatin for the treatment of advanced lung adenocarcinoma
| Side effects | Toxicity grade (WHO criteria)
|
|||
|---|---|---|---|---|
| I | II | III | IV | |
| Neutropenia | 15 (28.3%) | 6 (11.3%) | 6 (11.3%) | 0 |
| Thrombocytopenia | 9 (17%) | 5 (9.4%) | 0 | 0 |
| Hemoglobin reduction | 11 (20.8%) | 6 (11.3%) | 5 (9.4%) | 0 |
| Nausea/vomiting | 14 (26.4%) | 9 (17%) | 0 | 0 |
| Allergic reactions | 2 (3.8%) | 0 | 0 | 0 |
| Liver damage | 6 (11.3%) | 0 | 0 | 0 |
| Renal impairment | 2 (3.8%) | 0 | 0 | 0 |
| Hair loss | 12 (22.6%) | 4 (7.5%) | 0 | 0 |
Abbreviation: WHO, World Health Organization.