Comparisons between World Trade Center responders and Cogstate normative data. Dark gray, WTC responders with possible PTSD; White, WTC responders without possible PTSD; Light gray, normative comparison population. Two-tailed t tests were used to compare groups and to compare estimated age effects between groups. (A) Shows differences between WTC responders with and without PTSD and normal controls in memory. (B) Shows differences between WTC responders with and without PTSD and normal controls in reaction speed. (C) Shows differences between WTC responders with and without PTSD and normal controls in processing speed. *Significantly different compared to normative data when adjusting for the false discovery rate. Abbreviations: a/s, answers per second; PTSD, posttraumatic stress disorder; WTC, World Trade Center.