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. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Eur J Nucl Med Mol Imaging. 2017 Oct 30;45(1):132–150. doi: 10.1007/s00259-017-3839-5

Representative melanin-targeting probes. Chemical structures of (A) ¹²³I-BZA_2, (B) ¹²³I-MEL008, (C) ¹²³I-MEL037, (D) ¹²³I-53, and (E) ¹³¹I-IHPA. (F) MicroSPECT image of C57BL/6 mice bearing B16/F0 melanotic melanoma at 24 h postinjection of approximately 11.1 MBq of ¹²³I-IHPA, the tumor is indicated by the white arrow. Adapted and modified with permission from references [34, 36, 41, 42, 44].