Table 3. Credible SNPs for RRBs at 17q21, Candidate Target Genes and Spatiotemporal Expression pattern, Association with Subcortical Volume.
Credible SNP (Candidate Gene eQTL) | Candidate Gene (Function) | Spatiotemporal Expression Pattern | SNP Association with Subcortical Volume |
---|---|---|---|
rs2898883 (P<0.009) | SLC35B1 (Hi-C) | Thalamus, prenatal to postnatal stages | Thalamus, P=0.008 |
rs2233667 (P<0.01) | * | ||
| |||
rs7502499 (P>.05) | PHB (Promoter) | Thalamus, prenatal to postnatal stages Pan brain, childhood to adolescence (6-20 years) | Thalamus, P=0.01 |
| |||
rs71379361 (P>.05) | CALCOCO2 (Hi-C) | Pan brain, childhood (6-12 years) | Thalamus, P=0.01 |
chr17_47494782_D (*) | DLX3 (Hi-C) | * | * |
data not available,