Table 2.

Cytohistopathologic correlations in operated thyroid nodules

Study	Hospital	Year	Risk of malignancy for the Bethesda categories (%)						Nodule
			I	II	III	IV	V	VI
Young et al. (2011) [24]	St. Luke’s Medical Center, Quezon City	2007–2009	17.2	9.6		36.5a		76.5	251
Abelardo et al. (2011) [15]	Philippine General Hospital, Manila	2010	44.4	18.9	40.0	44.4	60.0	100.0	99
Canete et al. (2014) [19]	Philippine General Hospital, Manila	2008–2011	n/a	32.0	n/a	41.4	89.7	100.0	837
Carlos et al. (2014) [22]	St. Luke’s Medical Center, Quezon City	2012–2013	n/a	n/a	35.3	n/a	n/a	n/a	68
Ramos and Mirasol (2014) [16]	St. Luke’s Medical Center, Quezon City	2012–2013	33.3	13.5	22.2	33.3	72.2	100.0	175
Salillas et al. (2015) [23]	SWU-MHAM College of Medicine, Cebu City	2009–2012	n/a	2.6	50.0	50.0	78.0	100.0	80
Salillas and Almocera (2016) [25]	Private practice, Cebu City and Bohol	2010–2014	n/a	n/a	39.4	n/a	n/a	n/a	33
Abelardo and Abesamis (2016) [14]	The Medical City, Pasig City	2010–2015	n/a	26.5	n/a	n/a	71.4b		448
The Bethesda system reference rate [11]			1–4	0–3	5–15	15–30	60–75	97–99

n/a, not available.

^aSum of indeterminate categories III to V: classified as “indeterminate”;

^bOverall risk of malignancy for suspicious for malignancy and malignant cases.