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. 2017 Nov 15;51(6):588–593. doi: 10.4132/jptm.2017.08.10

Fig. 3.

Fig. 3.

Microscopic finding and immuohistochemical and fluorescence in-situ hybridization studies of metastatic ependymoma to the liver. (A) Results of the liver biopsy reveal metastatic anaplastic ependymoma. The metastatic tumor shows robust glial fibrillary acidic protein positivity (B) and high MIB-1 (Ki-67) labeling index of 92.47% (C). Fluorescence in-situ hybridization reveals low copy gain of 1q25 (1q25 [spectrum green]/1p36 [spectrum orange] ratio=1/55) (D) and CDKN2A (9p21.3) homozygous deletion (E).