Table 5.
The top 12 important pathways for DSGs.
| pathway | pvalue | gene |
|---|---|---|
| Thyroid hormone signaling pathway | 0.000438 | MED1/MED16/MED24/MYC |
| Apoptosis | 0.009077 | GADD45B/TNFSF10/LMNB2 |
| Cytosolic DNA-sensing pathway | 0.017271 | POLR2E/CCL4 |
| NF-kappa B signaling pathway | 0.036048 | GADD45B/CCL4 |
| Amoebiasis | 0.036744 | GNA15/GNA11 |
| Chagas disease (American trypanosomiasis) | 0.041034 | GNA15/GNA11 |
| Cholinergic synapse | 0.048583 | PIK3R5/GNA11 |
| Cytokine-cytokine receptor interaction | 0.05237 | CCL7/CCL4/TNFSF10 |
| Cell cycle | 0.058258 | GADD45B/MYC |
| FoxO signaling pathway | 0.065054 | GADD45B/TNFSF10 |
| Ubiquitin mediated proteolysis | 0.069434 | CDC34/UBE4B |
| Wnt signaling pathway | 0.074816 | MYC/TBL1XR1 |