Table 3.
Acute toxicities from chemoradiation treatment
| Value (%) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | |||||
| IMRT | 3D-CRT | IMRT | 3D-CRT | IMRT | 3D-CRT | IMRT | 3D-CRT | |
| Localized pain | 25 (41.0) | 28 (26.9) | 20 (32.8) | 47 (45.2) | 2 (3.3) | 12 (11.5) | 0 (0) | 1 (1.0) |
| Diarrhea | 19 (31.1) | 38 (36.5) | 14 (23.0) | 26 (25) | 4 (6.6) | 8 (7.7) | 0 (0) | 1 (1.0) |
| Fatigue | 20 (32.8) | 32 (30.8) | 15 (24.6) | 23 (22.1) | 0 (0) | 5 (4.8) | 0 (0) | 0 (0) |
| Dermatitis | 16 (26.2) | 22 (21.2) | 37 (60.7) | 58 (55.8) | 5 (8.2) | 19 (18.3) | 0 (0) | 0 (0) |
| Hematologic | 19 (31.1) | 43 (41.3) | 14 (23) | 24 (23.1) | 4 (6.6) | 15 (14.4) | 3 (4.9) | 4 (3.8) |
| Incontinence | 12 (19.7) | 30 (28.8) | 5 (8.2) | 16 (15.4) | 0 (0) | 2 (1.9) | 0 (0) | 1 (1.0) |
| Gastroenteritisa | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (1.0) | 1 (1.0) | 0 (0) | 0 (0) |
| Colitis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 | 2 (1.9) | 0 (0) | 0 (0) |
| Proctitis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 | 1 (1.0) | 0 (0) | 0 (0) |
| Fistula | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 | 2 (1.9) | 0 (0) | 0 (0) |
| Stenosis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 | 1 (1.0) | 0 (0) | 0 (0) |
IMRT intensity-modulated radiation therapy, 3D-CRT 3-dimensional conventional radiation therapy
aFrom treatment completion through 8 weeks post treatment