Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 23;7:16153. doi: 10.1038/s41598-017-16543-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fibronectin localization in SC-WATs of Egr1 ^+/+ and Egr1 ^−/− mice. SC-WATs of 1-month-old (A,B) and 4-months-old (C,D) Egr1 ^+/+ and Egr1 ^−/− mice were sectioned transversely and immuno-stained with Fibronectin FN (red) and UCP1 (green) antibodies. Nuclei were visualized with DAPI (blue). Individual channel or merged channels are indicated in panels. (A) Low magnifications show that FN (red) is less expressed in UCP1-positive areas (green) compared to UCP1-negative areas in 1-month-old Egr1 ^+/+ and Egr1 ^−/− mice. Scale bars, 200 µm. (B) High magnifications show that FN is absent around UCP1 + beige adipoctytes in 1-month-old Egr1 ^−/− compared to Egr1 ^+/+ mice, while being present around white adipoctyes in Egr1 ^+/+ mice. Scale bars, 50 µm. (C,D) At 4 months of age, FN is also absent around UCP1 + beige adipoctyes of SC-WATs from Egr1 ^−/−, while being present around white adipocytes in Egr1 ^+/+ mice. Scale bars, (C) 50 µm (D) 25 µm. (B–D) FN surrounds the regions of beige adipocytes.