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. 2017 Nov 23;7:16102. doi: 10.1038/s41598-017-16487-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Body weight control. (A) Weekly body weight of KAP Tg male mice (Tg) and control male littermates (c) fed on regular control diet (chow) or high fat diet (HFD). Results correspond to mean values from 3 independent set of experiments including n = 8 animals/group. Statistical analysis performed on area under the curve (AUC). *p < 0.05 between controls and Tg. #p < 0.05 between chow and HFD. (B) Weekly water (in grams) and food (kcal) intake. Results for this figure correspond to mean values from 1 experiment including control and Tg mice fed on regular chow or HFD (n = 8 per group). (C) Organ’s weight at the time of sacrifice at 7 months of life. Results correspond to mean values from 2 independent set of experiments including n = 8 animals/group. Significant differences between chow and HFD, ##p < 0.01. Error bars correspond to SEM.