Fig. 2.

An example of quantitative analysis of DCE-MRI data of a patient achieving pCR (top row) and a patient not achieving pCR (bottom row) before (first column), after the first cycle (second column), and at conclusion of all NAT (third column). The parametric map of $k_{\mathrm{ep}}$ overlaid on a high resolution anatomical MRI scan is shown. Note the diminution of $k_{\mathrm{ep}}$ exhibited in the patient achieving pCR after one cycle of NAT, but the enhanced $k_{\mathrm{ep}}$ in the patient not achieving pCR.