Fig. 3.

Exosomes release from sensory neurons is mediated by TRPV1 activation. a Representative western blot image and quantification of exosomal markers TSG101 and MFG-E8, in the media of cultured DRG neurons obtained from WT and TRPV1 KO mice and incubated with buffer control or CAPS for 3 h. b–e Expression of miRs in exosomal fraction of DRG media obtained from WT and TRPV1 KO mice. Data are means ± S.E.M., n = 4. *P < 0.05 compared to control WT, one-way ANOVA, post hoc Bonferroni test