Table 5.
Logistic regression analysis to predict the risk of CRC in non-CRC groups.
| Parameter | Coefficient | SE | P a value | ORa | OR (95% CI) |
|---|---|---|---|---|---|
| Univariate analysis | |||||
| HULC expression | 0.129 | 0.031 | <0.0001 | 1.137 | 1.07–1.207 |
| rs6983267 (GG vs GT/TT) | 0.837 | 0.295 | 0.005 | 2.3 | 1.295–3.533 |
| rs7763881 (AC vs AA) | −0.774 | 0.337 | 0.02 | 0.46 | 0.238–0.892 |
| Multivariate analysis | |||||
| HULC expression | 0.136 | 0.034 | <0.0001 | 1.146 | 1.073–1.224 |
| rs6983267 (GG vs GT/TT) | 0.932 | 0.319 | 0.004 | 2.538 | 1.358–4.761 |
| rs7763881 (AC vs AA) | −0.529 | 0.369 | 0.152 | 0.589 | 0.285–1.215 |
| Constant | −0.657 | ||||
Log likelihood of the stepwise multivariate logistic regression model = −144.39, −2 Log likelihood = 288.78, P < 0.0001. P a adjusted for age and sex. CRC, n = 120, non-CRC (healthy controls + AP), n = 126. P values in bold are statistically significant P < 0.05.