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. 2017 Nov 24;7:16278. doi: 10.1038/s41598-017-16446-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The molecular structure of ICAC and its effects on Vero cell viability. (A) The molecular structure of ICAC. (B) The compound was diluted to various concentrations as indicated in triplicate. The cytotoxicity of ICAC was determined by MTS assay after incubation with the drug for 48 h. The cell viability in DMEM without ICAC (control) was set as 100% (n = 6). All results were expressed as the means ± SEs. Asterisks indicate that the data significantly differ from the control group at the P < 0.05 level according to one-way analysis of variance.