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. 2017 Nov 24;7:16286. doi: 10.1038/s41598-017-16490-3

Figure 1.

Figure 1

PM2.5 exposure induces hepatic steatosis in normal chow diet-fed mice but relieves hepatic steatosis in HF-fed mice. (A) Oil-red O staining of lipid droplets in the livers of the normal chow (NC)- or HF diet (HFD)- fed mice exposed to PM2.5 or FA for 10 weeks (magnification: 200x). (B) Levels of hepatic TG in the liver tissues of NC- or HFD- fed mice exposed to PM2.5 or FA for 10 weeks. N = 6 mice for PM2.5- or FA- exposed group under HFD; or 4 mice for PM2.5-or FA-exposed group under NC. Each bar denotes mean ± standard deviation (SD). *p < 0.05. (C) Photograph of blood-plasma samples from the representative NC- or HFD- fed mice after 10-week exposure to PM2.5 or FA. (D–H) Levels of blood TG (D), LDL/VLDL (E), total cholesterol (F), AST (G), and ALT (H) in NC- or HFD- fed mice exposed to PM2.5 or FA for 10 weeks. LDL/VLDL, low and very low density lipoproteins. Each bar denotes mean ± SD. *p < 0.05; **p < 0.01.