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. 2017 Nov 24;7:16217. doi: 10.1038/s41598-017-16522-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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SAPP-mediated inhibition of oral keratinocyte invasion by P. gingivalis. Invasion of human oral keratinocytes (HOKs) by P. gingivalis was determined by an antibiotic protection assay. P. gingivalis 33277 (a) or W83 (b) were grown with 24 or 48 µM SAPP, respectively. The number of internalized P. gingivalis cells was represented with means ± SD of triplicates. An asterisk indicates a significant difference between invasive levels observed for P. gingivalis cells grown with or without SAPP (p < 0.05; t test).