Table 2.
Prognostic factors and their independent associations with biochemical failure in prostate tissue in 535 prostate cancer patients (multivariate analyses; Cox regression with backward conditional model).
| Characteristics | Patients | Biochemical failure | ||
|---|---|---|---|---|
| (n) | (%) | HR (95% CI) | p | |
| CAPRA-S Score | <0.001 | |||
| 0–2 | 169 | 32 | 1 | |
| 3–5 | 258 | 48 | 1.83 (1.19–2.81) | |
| 6–12 | 102 | 19 | 4.55 (2.88–7.20) | |
| Missing | 6 | 1 | — | |
| Tumor size | NS | |||
| 0–20 mm | 250 | 47 | ||
| >20 mm | 285 | 53 | ||
| Perineural infiltration | 0.001 | |||
| No | 250 | 47 | 1 | |
| Yes | 285 | 53 | 1.78 (1.27–6.93) | |
| Lymphovascular infiltration | NS | |||
| No | 492 | 92 | ||
| Yes | 43 | 8 | ||
| miR-205 in epithelium | 0.001 | |||
| Low expression | 220 | 41 | 1 | |
| High expression | 245 | 46 | 1.70 (1.23–2.35) | |
| Missing | 70 | 13 | — | |
Abbreviations: HR = hazard ratio; NS = not significant and removed by backward model before last step of analyses.