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. 2017 Nov 24;7:16231. doi: 10.1038/s41598-017-13431-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relative ANRIL expression levels and their association with poor clinical outcome in OSCC tissues. (a) Relative ANRIL expression levels in paired OSCC samples were detected by qPCR. (b) Related ANRIL expression levels of human oral squamous cancer cell OSCC3, SCC4, HSC3 and CAL27 compared with that in human immortal keratinocyte line HaCaT. The association between the expression of ANRIL in tumour samples and TNM (c) or lymph node metastasis (d) was analysed (*P < 0.05, **P < 0.01, ***P < 0.001).