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. 2017 Nov 24;7:16207. doi: 10.1038/s41598-017-16498-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ultrastructural analysis of WT and rbpr2 ^musc97 mutant photoreceptors. Transmission electron microscopy provided ultrastructural views of WT and rbpr2 ^musc97 mutant photoreceptor cells at 5.5 dpf. (A,C,E and G) WT photoreceptors exhibit tightly stacked outer segment membranes (panels A,C and E; arrows) and RPE cells containing many melanosomes (C); (B,D,F and G) while in rbpr2 ^musc97 mutants only remnants of outer segments (panels B and F; arrows) could be observed, with fewer melanosomes in the RPE cells (D). Scale bars = 800 nm (A–E); 400 nm (F); 200 nm (G and H). OS, outer segments; RPE, Retinal Pigmented Epithelium.