Table 1.
Summary of the uptake inhibition of SiNPs in the presence of endocytic inhibitors.
| Inhibitor | Function | SiNP-OH | SiNP-NH2 | SiNP-COOH | |||
|---|---|---|---|---|---|---|---|
| MCF-7 | BCSC | MCF-7 | BCSC | MCF-7 | BCSC | ||
| cyto D | Inhibits F-actin polymerization | ++ | + | ++ | + | ++ | + |
| Nocodazole | Disruption of microtubules | − | − | − | − | − | − |
| CPZ | Inhibits clathrin | + | + | + | + | + | + |
| Dynasore | Inhibits dynamin-GTPase | − | − | − | − | − | − |
| Nystatin | Lipid-raft inhibitor | − | − | − | − | − | − |
| Poly I | Scavenger receptor inhibitor | − | ++ | − | ++ | − | ++ |
| Genistein | Inhibitor of several tyrosine kinases | − | − | − | − | − | − |
+p < 0.05, ++p < 0.01 through unpaired t-test between control and inhibitor-treated groups. − no significant inhibition.