Table 2.

Circadian amplitude of central and peripheral markers.

Marker	Treatment	Condition	Amplitude (nonlinear mixed procedure)	P value
Cortisol	Control	Baseline	7.7 ± 0.6	0.04
		Night shift	5.6 ± 0.6
	Bright light	Baseline	6.8 ± 0.7	0.54
		Night shift	6.2 ± 0.7
Melatonin	Control	Baseline	35.4 ± 2.7	0.12
		Night shift	28.9 ± 2.7
	Bright light	Baseline	28.2 ± 1.7	0.89
		Night shift	27.9 ± 1.7
PER1	Control	Baseline	0.9 ± 0.1	0.06
		Night shift	0.5 ± 0.1
	Bright light	Baseline	0.4 ± 0.1	0.85
		Night shift	0.5 ± 0.1
PER2	Control	Baseline	0.7 ± 0.1	0.03
		Night shift	0.3 ± 0.1
	Bright light	Baseline	0.8 ± 0.1	0.46
		Night shift	0.6 ± 0.1
PER3	Control	Baseline	1.2 ± 0.1	0.004
		Night shift	0.6 ± 0.1
	Bright light	Baseline	0.4 ± 0.1	0.52
		Night shift	0.5 ± 0.1
BMAL1	Control	Baseline	0.8 ± 0.1	0.07
		Night shift	0.5 ± 0.1
	Bright light	Baseline	0.5 ± 0.1	0.23
		Night shift	0.3 ± 0.1
REV-ERBα	Control	Baseline	1.1 ± 0.1	0.003
		Night shift	0.6 ± 0.1
	Bright light	Baseline	0.8 ± 0.1	0.04
		Night shift	0.4 ± 0.1