Fig. 7.

X-ray examination after 2 years of suspension of zoledronic acid treatment in the male proband. Marked improvement of diaphyseal thickening and cortical sclerosis of femurs (a), tibiae and fibulae (b), and right humerus (c) is shown. The morphology of the medullary cavity was more regular, mainly at femurs and tibiae. The typical multiple zebra lines related to the previous intravenous bisphosphonates infusions were less evident and tended to disappear as they move into the diaphysis secondary to bone remodeling.