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. Author manuscript; available in PMC: 2017 Nov 24.
Published in final edited form as: J Infect Dis. 2015 Jul 14;212(10):1684–1685. doi: 10.1093/infdis/jiv385

Table 2.

Influenza Vaccination and Severity of Influenza Disease Analysis for Cases Treated With Antivirals by Age Category, After Propensity Score Matching (n = 1509)a

Clinical Outcomes Influenza Vaccine 2012–13 Season

50–64 y (n = 494) 65–74 y (n = 495) ≥75 y (n = 520)



Point Estimate (95% CI) P Value Point Estimate (95% CI) P Value Point Estimate (95% CI) P Value
Severe diseaseb (OR) 0.97 (.62; 1.52) .89 1.27 (.81; 1.99) .29 0.99c (.59; 1.66) .97

Diagnosis of pneumoniad (OR) 0.79 (.54; 1.18) .25 0.86c (.59; 1.26) .44 0.94c (.65; 1.35) .72

ICU length of stay (RH)e 1.25 (.82; 1.91) .3 1.60 (1.04; 2.46) .03 0.94 (.50; 1.77) .85

Length of hospital stay (RH)e 1.03 (.88; 1.21) .69 1.03 (.88; 1.21) .68 1.02 (.87; 1.19) .80

Abbreviations: BMI, body mass index; CI, confidence interval; ICU, intensive care unit; OR, odds ratio; RH, relative hazard.

a

Variables used for propensity score matching: sex, race, BMI, medical condition (asthma, chronic lung disease, cardiovascular disease, chronic metabolic disease, neurologic disease, immunosuppression, hemoglobinopathy/blood disorders, renal disease, liver disease), alcohol abuse, and smoking.

b

Admitted to ICU or deceased.

c

Adjusted for the Charlson score.

d

Among those who had a chest X-ray taken within 3 days of admission (n = 1,460).

e

RH represents ICU or hospital discharge accounting for death as a nonindependent competing risk.