Table 8.
Up/Down-regulatedc | Regulated by | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Genea | Enzymeb | CAZy family | ΔxlnR | ΔaraR | ΔrhaR | ΔgalX | ΔamyR | This study | Literature | Reference | |
F-1 | An02g00610 | GUS | GH2 | 11.7 | – | – | – | – | nd | nr | [38] |
An09g03070 (agsE) | AGS | GH13 | 1.6 | 1.1 | −2.0 | −11.0 | −5.8 | AmyR, GalX | nr | [43, 75] | |
An16g02730 (abnD) | ABN | GH43 | 3.6 | – | – | – | −2.5 | AmyR | GaaR, RhaR | [15, 34, 39] | |
An09g00260/An09g00270 (aglC) | AGL | GH36 | 1.3 | 1.0 | −3.5 | 1.3 | 1.3 | RhaR | AmyR | [8, 44] | |
F-2 | An09g05350 | FAE | SF9d | 1.5 | – | – | – | −1.1 | nd | nr | [4] |
aGenes with expression value of <50 in all studied A. niger N402 cultures are not included in the table
bEnzyme codes are provided in Additional file 2
cFold-change between A. niger N402 and the regulatory mutants grown on their relevant carbon source. - = expression value <50 in both N402 and regulatory mutant strain. Negative fold-changes >2.5 were considered proof of regulator function and are depicted in bold
dSub-family (SF) classification of fungal FAEs according to Dilokpimol et al. [49]
nd not detected, nr not reported