Table 2.
Genotype and minor allele frequencies of the SNPs at LPL and APOE genes in the DIVAS cohort of adults with moderate CVD risk
| SNP | MAF | Common homozygous N (%) | Heterozygous N (%) | Rare homozygous N (%) |
|---|---|---|---|---|
| LPL | ||||
| rs320 (T > G) | 0.30 | 56 (0.47) | 54 (0.45) | 9 (0.07) |
| rs328 (C > G) | 0.13 | 89 (0.74) | 30 (0.25) | 1 (0.008) |
| APOE | ||||
| rs405509 (G > T) | 0.47 | 31 (0.25) | 64 (0.53) | 25 (0.20) |
| rs769450 (G > A) | 0.37 | 44 (0.36) | 61 (0.50) | 15 (0.12) |
| rs439401 (C > T) | 0.35 | 50 (0.42) | 52 (0.44) | 16 (0.13) |
| rs445925 (G > A) | 0.11 | 91 (0.77) | 25 (0.21) | 1 (0.008) |
| rs405697 (G > A) | 0.25 | 70 (0.58) | 38 (0.31) | 11 (0.09) |
| rs1160985 (C > T) | 0.45 | 33 (0.27) | 64 (0.53) | 23 (0.19) |
| rs1064725 (T > G) | 0.05 | 108 (0.90) | 12 (0.10) | – |
MAF minor allele frequency, LPL lipoprotein lipase, APOE apolipoprotein E