Table 5.
Changes in lipid levels after dietary intervention over 16 weeks according to LPL rs320 genotypes
| SFA | MUFA | n-6 PUFA | Pinteraction | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| TT (N = 21) | G allele (N = 20) | Passociation | TT (N = 11) | G allele (N = 24) | Passociation | TT (N = 24) | G allele (N = 19) | Passociation | ||
| Total cholesterol | 0.37 ± 0.60 | 0.29 ± 0.45 | 0.59 | 0.21 ± 2.66 | −0.67 ± 2.07 | 0.21 | −0.32 ± 1.67 | −0.12 ± 0.64 | 0.92 | 0.34 |
| TAG | −0.04 ± 2.35 | 0.07 ± 0.59 | 0.84 | 0.04 ± 0.50 | 0.01 ± 0.29 | 0.58 | −0.07 ± 0.32 | −1.19 ± 2.78 | 0.02 | 0.15 |
| HDL-C | 0.09 ± 0.15 | 0.01 ± 2.33 | 0.94 | −0.07 ± 0.17 | 0.03 ± 0.15 | 0.04 | 0.02 ± 0.25 | 0.43 ± 2.91 | 0.78 | 0.75 |
| LDL-C | 0.29 ± 2.71 | 0.27 ± 0.40 | 0.95 | −1.70 ± 2.85 | 0.16 ± 2.22 | 0.11 | 0.91 ± 2.23 | −1.00 ± 2.50 | 0.007 | 0.005 |
P values for association between genotypes and changes of means over 16 weeks with one of three diets were obtained by using general linear model adjusted for age, sex, body mass index, and ethnicity. P values for interaction between genotypes and changes of means over 16 weeks of intervention with one of three diets were obtained by using general linear model adjusted for age, sex, body mass index, and ethnicity. Values are mean ± SD
TAG triacylglycerol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, SFA saturated fatty acids, MUFA monounsaturated fatty acids, PUFA polyunsaturated fatty acids