Table 2.
Clinicopathological data of patients with EGC and univariate analysis of risk factors for lymph node metastasis
| LNM- | LNM+ | p | Odds ratio (95% CI) | ||
|---|---|---|---|---|---|
| Gender | Male | 99 (84.6%) | 18 (15.4%) | p = 0.090 | 1.80 (0.92–3.55) |
| Female | 76 (75.2%) | 25 (24.8%) | |||
| Age | 65.26 ± 12.17 | 66.91 ± 13.03 | p = 0.433 | – | |
| Tumor localization | Lower 1/3 | 62 (78.5%) | 17 (21.5%) | p = 0.457 | – |
| Middle1/3 | 100 (80.0%) | 25 (20.0%) | |||
| Upper 1/3 | 13 (92.9%) | 1 (7.1%) | |||
| Tumor invasion | T1a | 94 (94.9%) | 5 (5.1%) | p = 0.001 | 8.82 (3.31–23.46) |
| T1b | 81 (68.1%) | 38 (31.9%) | |||
| Tumor differentiation | G1 & G2 | 100 (87.7%) | 14 (12.3%) | p = 0.006 | 2.76 (1.36–8.57) |
| G3 | 75 (72.1%) | 29 (22.4%) | |||
| Lymphovascular invasion | LV+ | 12 (40%) | 18 (60%) | p = 0.001 | 9.78 (4.20–22.72) |
| LV- | 163 (86.7%) | 25 (13.3%) | |||
| Lauren classification | Diffuse & mix | 59 (71.1%) | 24 (28.9%) | p = 0.012 | 2.09 (1.20–3.64) |
| Intestinal | 106 (86.2%) | 17 (13.8%) | |||
| Tumor size | ≤2 cm | 91 (86.7%) | 14 (13.3%) | p = 0.026 | 2.27 (1.12–4.59) |
| >2 cm | 83 (74.1%) | 29 (25.9%) | |||
| Ulceration | Ulcerated | 58 (74.4%) | 20 (25.6%) | p = 0.114 | 1.73 (0.88–3.42) |
| Non-ulcerated | 116 (83.5% | 23 (16.5%) | |||
| Signet ring cell | Yes | 11 (73.3%) | 4 (26.7%) | p = 0.513 | 1.46 (0.44–4.86) |
| No | 149 (80.1%) | 37 (19.9%) | |||