Table 2.

Characterization of fever in patients who develop CRS

Fever	CRS grade												P*
	1-3				4-5				Total
	No.	Median	IQR	Range	No.	Median	IQR	Range	No.	Median	IQR	Range
No. of patients	83				10				92
Fever onset (days after CAR T-cell infusion)		3.9	0.8-5.6	0.1-19		0.4	0.3-0.9	0.2-1.0		2.2	0.9-5.6	0.1-19	<.0001
Time to peak temperature (days after CAR T-cell infusion)		5.7	4.3-7.6	0.2-30		2.8	1.3-3.2	0.4-11		5.3	3.4-7.3	0.2-30	.001
Maximum temperature (°C)		39.4	39.2-39.6	37.7-41.3		40.4	40.1-40.6	39.9-40.9		39.5	39.2-39.8	37.7-41.3	<.0001
Fever duration (days after first fever)		2.5	1.2-4.7	0.02-15		4.4	3.6-5.4	3.1-6.8		3.0	1.2-4.8	0.02-15	.03

^*Two-sided P values were calculated by using the Wilcoxon test.