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Effect of CXL-1020 on isolated cardiomyocyte function in the ISO rat model. (A) Representative trace of Ca2+ transients (CaT) and myocyte shortening (as the % resting cell length (RCL)). (B) Summary data as % change from baseline of contractile changes (n = 14 cells/7 hearts) (CaT and shortening amplitude) and relaxation (CaT and relengthening RT50), *P < 0.05 vs. corresponding baseline.
