Table 1.
Klebsazolicin MICs for various bacterial strains in rich LB medium and minimal M9+Glucose medium.
| Microorganism (Strain) | MIC, μg/ml | MIC, μM | |
|---|---|---|---|
| LB medium | Escherichia coli B | 32 | 16 |
| Escherichia coli K-12 MG1655 | 128 | 65 | |
| Escherichia coli MG1655 (ΔompF) | 256 | 130 | |
| Escherichia coli MG1655 (ΔsbmA) | >1024 | >519 | |
| Escherichia coli MG1655 (pBAD-sbmA-ompF) | 64 | 32 | |
| Escherichia coli MG1655 (pBAD-klpE) | 1024 | 519 | |
| Yersinia pseudotuberculosis | 64 | 32 | |
| Klebsiella pneumoniae | 128 | 65 | |
| Vibrio cholerae | >1024 | >519 | |
| Acinetobacter baumannii | >1024 | >519 | |
| Pseudomonas aeruginosa | >1024 | >519 | |
| Pseudomonas putida | >1024 | >519 | |
| Staphylococcus aureus | >1024 | >519 | |
| Bacillus subtilis | >1024 | >519 | |
| Bacillus cereus | >1024 | >519 | |
| Mycobacterium smegmatis | >1024 | >519 | |
| Listeria grayi | >1024 | >519 | |
| Streptomyces lividans | >1024 | >519 | |
| M9+Glucose | Escherichia coli B | 4 | 2 |
| Escherichia coli K-12 MG1655 | 16 | 8 | |
| Klebsiella pneumoniae | 64 | 32 |