Table I.

Characteristics of studies of the vitamin D receptor (VDR) FokI gene polymorphism included in this meta-analysis

First author	Year	Ethnicity	Source of control	Genotyping	Sample size of case				Sample size of control				PHWE	Frequencyof f allele
					ff	fF	FF	Total	ff	fF	FF	Total
Correa	1999	Caucasian	Population-based	PCR-RFLP	10	58	50	118	9	42	38	89	0.598	0.337
Chokkalingam	2001	Asian	Hospital-based	PCR-RFLP	41	95	51	187	62	153	87	302	0.725	0.459
Tayeb	2004	Caucasian	Population-based	PCR-RFLP	2	10	16	28	11	24	21	56	0.391	0.411
Oakley-Girvan	2004	Caucasian	Population-based	PCR-RFLP	27	120	85	232	26	77	68	171	0.586	0.377
Oakley-Girvan	2004	African-American	Population-based	PCR-RFLP	4	25	84	113	5	42	74	121	0.752	0.215
Bodiwala	2004	Caucasian	BPH-based	PCR-RFLP	60	163	145	368	35	100	108	243	0.137	0.350
Cheteri	2004	Caucasian	Population-based	PCR-RFLP	101	247	204	552	80	234	207	521	0.305	0.378
Mishra	2005	Arabian	Hospital-based	PCR-RFLP	5	45	78	128	16	69	62	147	0.622	0.344
John	2005	Caucasian	Population-based	PCR-RFLP	69	203	153	425	57	209	171	437	0.581	0.370
Hayes	2005	Caucasian	Population-based	DGGE	112	359	340	811	98	322	293	713	0.526	0.363
Cicek	2006	Mixed	Population-based	PCR-RFLP	71	191	77	339	77	202	200	479	0.034	0.372
Huang	2006	Asian	Hospital-based	PCR-RFLP	87	204	125	416	119	248	135	502	0.806	0.484
Rukin	2007	Caucasian	BPH-based	Pyrosequencing	166	203	61	430	135	141	44	320	0.461	0.642
Mikhak	2007	Caucasian	Population-based	Taqman	101	337	232	670	108	310	255	673	0.398	0.391
Li	2007	Caucasian	Population-based	PCR-RFLP	152	475	383	1010	206	655	571	1432	0.413	0.373
Holick	2007	Caucasian	Population-based	SNPlex assay	100	261	222	583	85	245	222	552	0.204	0.376
Torkko	2008	Spanish	Population-based	Taqman	26	70	45	141	57	125	91	273	0.249	0.438
Torkko	2008	Caucasian	Population-based	Taqman	67	209	168	444	63	227	198	488	0.87	0.362
Holt	2009	African-American	Population-based	SNPlex assay	2	48	65	115	4	24	39	67	0.904	0.239
Holt	2009	Caucasian	Population-based	SNPlex assay	108	335	262	705	101	352	263	716	0.332	0.387
Bai	2009	Asian	Hospital-based	PCR-RFLP	26	63	33	122	37	55	38	130	0.08	0.496
Rowland	2013	African-American	Population-based	Taqman	24	161	236	421	10	90	134	234	0.287	0.235
Rowland	2013	Caucasian	Population-based	Taqman	193	598	406	1197	112	413	311	836	0.171	0.381
Yousaf	2014	Arabian	Hospital-based	PCR-RFLP	2	0	39	41	13	0	95	108	0	0.120
Atoum	2015	Arabian	Population-based	PCR	10	76	38	124	6	66	28	100	0	0.390

HWE – Hardy-Weinberg equilibrium of controls, RFLP – restriction fragment length polymorphism, BPH – benign prostatic hyperplasia.