Figure 1.

Immunohistochemical (A–C) and hybridocytochemical localization of β-catenin (D) in liver. Membranous/ cytoplasmic localization of β-catenin in liver with chronic hepatitis C (A), membranous localization of β-catenin in hepatocellular carcinoma (B) and in control liver (C); mRNA for β-catenin in cytoplasm and cell nuclei in HCC fragment (D). Immunocytochemical detection of E-cadherin (E–F) and N-cadherin (H) in liver. Predominantly membranous localization of E-cadherin in liver with chronic hepatitis C (E), hepatocellular carcinoma (F) and control liver (G). Membrano-cytoplasmic localization of N-cadherin in fragment of hepatocellular carcinoma (H). Immunohistochemistry (A–C, E–H) technique and hybridization in situ method (D). Hematoxylin counterstained. Bar = 40 μm