TABLE 1.
Anthropometric, hematologic, and biochemical outcomes of iron-supplemented and unsupplemented iron-replete and non–iron-replete infants at the 12-mo follow-up1
| Iron replete (n = 154)2 |
Non–iron replete (n = 452) |
|||||
| Fe (n = 80) | Nonsupplemented (n = 74) | P3 | Fe+ (n = 220) | Fe− (n = 232) | P4 | |
| WAZ5 | −1.99 ± 1.02 | −1.58 ± 1.13 | <0.001 | −1.60 ± 1.03 | −1.63 ± 1.05 | 0.45 |
| ΔWAZ5 | −1.45 ± 0.46 | −1.03 ± 0.63 | <0.001 | −1.23 ± 0.56 | −1.27 ± 0.54 | 0.44 |
| WLZ5 | −1.37 ± 1.17 | −0.85 ± 1.27 | 0.001 | −0.87 ± 1.10 | −0.89 ± 1.06 | 0.39 |
| LAZ5 | −0.79 ± 1.05 | −0.83 ± 0.93 | 0.83 | −0.79 ± 0.84 | −0.82 ± 0.92 | 0.68 |
| Hemoglobin,5 g/L | 119.2 ± 15.3 | 117.6 ± 15.4 | 0.43 | 116.7 ± 14.9 | 113.6 ± 15.8 | 0.03 |
| SF,6 μg/L | 47.5 ± 2.0 | 20.7 ± 2.2 | 0.04 | 36.8 ± 2.6 | 11.7 ± 3.7 | <0.001 |
| Serum zinc,5 μmol/L | 9.7 ± 2.5 | 10.5 ± 3.1 | 0.04 | 10.3 ± 3.3 | 10.9 ± 4.1 | 0.12 |
1
Adapted from Lind et al. (13) with permission. Fe−, no Fe provided; Fe+, Fe drops; LAZ, length-for-age z score; SF, serum ferritin; WAZ, weight-for-age z score; WLZ, weight-for-length z score; ΔWAZ, weight-for-age change from baseline to follow-up.
2
Hemoglobin concentration ≥113 g/L and SF concentration ≥33 μg/L at 6 mo of age.
3
ANOVA for difference between Fe+ and Fe− iron-replete infants.
4
ANOVA for difference between Fe+ and Fe− non–iron-replete infants.
5
All values are means ± SDs.
6
All values are antilogs of mean ln values ± SDs.