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. 2017 Nov 24;28(1):010704. doi: 10.11613/BM.2018.010704

Table 2. Comparison of laboratory values measured in serum for different centrifugation conditions.

Parameter N* CV (%) Centrifugation conditions P
2000xg/10min 3000xg/7min 3000xg/5min
Free haemoglobin, g/L 41 / 0.05 (0.03) 0.07 (0.04) 0.07 (0.03) 0.001
Icterus index, index 41 / 1 (0) 1 (0) 1 (0) 0.99
Lipemia index serum, index 41 / 5 (4) 6 (5) 6 (5) 0.99
Anti-Müllerian hormone, pmol/L 37 (4) 4.4 25.7 (23.5) 25.7 (23.5) 25.7 (23.5) 0.99
Prealbumin, µmol/L 41 5.7 4.8 (1.4) 4.9 (1.1) 4.8 (1.5) 0.99
Carcinoembryonic antigen, U/L 38 (3) 10.2 23.7 (16.1) 23.7 (14.8) 23.7 (14.8) 0.99
Alpha Fetoprotein, U/L 38 (3) 7.4 19.9 (13.1) 19.9 (14.5) 19.9 (12.9) 0.99
Cytokeratin fragment 21-1, µg/L 41 6.1 1.2 (0.7) 1.2 (0.8) 1.2 (0.7) 0.99
Cancer-Antigen 125, U/L 41 5.7 120 (60) 120 (80) 120 (70) 0.99
Cancer-Antigen19-9, U/L 41 6.2 70 (150) 70 (150) 60 (150) 0.99
Cancer-Antigen 15-3, U/L 41 6.4 170 (110) 170 (100) 170 (110) 0.99
S100 protein, µg/L 41 7.2 0.05 (0.02) 0.05 (0.02) 0.05 (0.02) 0.99
Neuron specific enolase, µg/L 41 6.2 11 (3) 12 (3) 12 (3) 0.71
Cancer-Antigen 72-4, U/L 41 6.5 13 (37) 13 (36) 13 (37) 0.99
Cystatin C, nmol/L 41 2.9 62.9 (11.2) 62.9 (12) 62.9 (12.7) 0.99
Cystatin C estimated glomerular filtration rate, mL/min/1.73m2 41 / 97 (19) 99 (19) 98 (20) 0.99
Soluble fms-like tyrosine kinase-1, pg/mL 41 16.0 89.4 (11.7) 89.9 (11) 88.8 (13.1) 0.99
Placental growth factor, pg/mL 41 16.8 14.89 (4.5) 14.64 (4.2) 14.95 (4.2) 0.99
sFlt1/PlGF Ratio, ratio 41 / 6.29 (1.6) 6.4 (1.6) 6.4 (1.6) 0.99
Data are presented as median and interquartile range. P < 0.05 was considered statistically significant. *Amount of individual samples used for calculation. In those parameters where this value is less than 41, some of the samples had measured values below the measuring range of the respective assay. The number of excluded samples, where applicable, are shown in parentheses. All assays were performed on a COBAS 8000 instrument (Roche Diagnostics) using only proprietary reagents. CVs of day-to-day QC control values of the respective parameter. CV – coefficient of variation.