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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Trends Genet. 2017 Sep 22;33(12):971–978. doi: 10.1016/j.tig.2017.09.001

Figure 3. Fusome-mediated sharing of death-promoting signal may enhance sensitivity of spermatogonia to DNA damage.

Figure 3

A. In the Drosophila testis, all spermatogonia within a cyst die in synchrony even when only a subset of spermatogonia have DNA damage. This is mediated by the fusome, as spermatogonia die individually in fusome mutants.

B. The fusome might facilitate the sharing of death-promoting signal among spermatogonia, leading to all-or-none cell death.