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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: J Invest Dermatol. 2017 Aug 12;137(12):2473–2483. doi: 10.1016/j.jid.2017.06.032

Table 2B.

Changes in Levels of Skin Biomarkers (i.e., COMP and THBS1) at Day-28 after enrollment from that at baseline according to treatment assignment

Biomarkers (log value)* Placebo (n=16) C-82 (n=14) P value
Mean of Change (SD) Mean of Change (SD)
COMP −0.062 (0.614) −0.345 (0.808) >0.283
THBSI 0.078 (0.541) −0.130 (0.496) >0.285
Local Skin Score Placebo (n=17) Treatment (n=17) P value
Mean of Change (SD) Mean of Change (SD)
−0.176 (0.529) −0.059 (0.659) 0.766
*

Subject 107 had missing value for biomarkers on 28-day after enrollment of the study. Subject 301 had missing value for biomarkers at baseline of the study. Subject ID=304 was excluded from biomarker analysis prior to data lock due to an outlier value.