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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Clin J Pain. 2018 Feb;34(2):182–189. doi: 10.1097/AJP.0000000000000517

Table 2.

Unadjusted/Adjusted means for each PUFA for low & high n-6:n-3 PUFA ratio groups

Low Ratio
n = 42
High Ratio
n = 41
Group Difference
Mean 95% CI Mean 95% CI F-value p-value
Lower
Bound
Upper
Bound
Lower
Bound
Upper
Bound
Omega-3
DHA% 6 5.14 6.67 2 1.09 2.64 54.48 <.0001
6.31 5.32 7.30 2.13 0.99 3.27 48.76 <.0001
ALA% 10 9.34 11.33 7 6.14 8.16 20.14 <.0001
9.67 8.38 10.95 6.66 5.18 8.14 14.91 0.0002
EPA% 1 1.04 1.38 0 0.15 0.50 49.99 <.0001
1.19 0.96 1.41 0.36 0.09 0.62 36.99 <.0001
Sum% 17 16.35 18.56 9 8.23 10.46 105.43 <.0001
17.17 15.73 18.61 9.14 7.48 10.80 84.45 <.0001
Omega-6
AA% 8 6.58 9.40 4 2.71 5.56 14.7 0.0002
9.76 8.13 11.39 5.85 3.97 7.73 15.66 0.0002
LA% 75 72.63 76.48 87 84.58 88.47 75.53 <.0001
73.07 70.72 75.42 85.01 82.30 87.72 70.20 <.0001
Sum% 83 81.45 83.65 91 89.54 91.77 105.38 <.0001
82.84 81.40 84.28 90.86 89.20 92.52 84.43 <.0001
n-6:n-3 Ratio
n-6:n-3 ratio 5 4.65 5.38 10 9.47 10.21 337.73 <.0001
5.08 4.61 5.56 9.92 9.37 10.47 280.96 <.0001

Adjusted (italics) and unadjusted (bold), controlling for ethnicity, age, sex, and study site yielded similar findings.