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Inhibitory profile of chemical inhibitors on vicagrel hydrolase activity. BNPP (1 mM) is a non-selective inhibitor of esterases; loperamide (20 μM) is a specific inhibitor of CES2; vinblastine and eserine (both 20 μM) are selective inhibitors of AADAC; simvastatin, atorvastatin, and benzbromarone are strong inhibitors of CES and AADAC.
