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. 2017 Nov 20;8:321. doi: 10.3389/fendo.2017.00321

Figure 2.

Figure 2

Average serum levels of free thyroxine (FT4) (pg/ml; mean ± SD and, in brackets, median) in patients stratified based on formulation of l-thyroxine. NF, novel formulation (either liquid oral solution or softgel capsule); OLS, oral liquid solution; SGC, softgel capsule. With reference to the first pair of bars, omitting patient #7 (whose postswitch serum FT4 level failed to reach the midnormal range value), the 21 preswitch and the 13 postswitch FT4 measurements averaged 11.84 ± 1.96 and 14.19 ± 2.15 pg/ml (P = 0.0025), with corresponding median levels of 11.5 and 14.06 pg/ml. Omitting patient #4 (whose preswitch FT4 level already passed the midnormal range value), the 20 preswitch and the 13 postswitch FT4 measurements averaged 10.45 ± 1.79 (median = 10.6) and 12.97 ± 1.58 pg/ml (median 13.9) (P = 0.0004).