Table 3.

ROC analysis for in-hospital and 2.5-year MACEs

Parameters	AUC	95% CI	P Value	Threshold	Sensitivity, %	Specificity, %
2.5-year MACEs
Δapelin-12	0.547	0.500 to 0.593	0.0906	20%	91.53	30.64
apelin-12	0.619	0.573 to 0.663	0.0001*	0.87	75.36	42.03
eGFR	0.565	0.518 to 0.611	0.0369*	86.13	53.39	63.87
LVEF	0.597	0.551 to 0.642	0.0015*	50%	59.32	56.94
Apelin-12>0.76 ng/mL
Δapelin-12	0.530	0.454 to 0.605	0.4767	17%	92.31	39.81
Apelin-12≤0.76 ng/mL
Δapelin-12	0.613	0.547 to 0.675	0.0075*	20%	100.00	30.77
In-hospital MACEs
Δapelin-12	0.507	0.460 to 0.553	0.8711	20%	3.23	73.44
apelin-12	0.623	0.577 to 0.667	0.0169*	0.64	51.61	70.67
eGFR	0.543	0.497 to 0.589	0.4021	86.98	58.06	59.12
LVEF	0.674	0.629 to 0.716	0.0005*	52%	83.87	43.42

*Statistically significant value (P<0.05).

AUC, area under curves; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; MACEs, major adverse cardiovascular events; ROC, receiver operating characteristic.