Table 3.
Missense and nonsense variants that were significantly (p < 5*10−9) associated with calving traits
| Trait | BTA | Position | p-value | Gene | Variant | PolyPHEN2 | SIFT |
|---|---|---|---|---|---|---|---|
| CEd | 25 | 1,277,577 | 5.59 × 10−10 | CRAMP1L | p.R885Q | probably damaging | deleterious |
| CEd | 25 | 1,177,995 | 1.93 × 10−9 | TELO2 | p.R536W | probably damaging | deleterious |
| CEd | 25 | 1,161,904 | 4.05 × 10−9 | PTX4 | p.P207L | probably damaging | tolerated |
Trait: CEd calving ease direct
BTA: Chromosome
P-value: From GWAS with EMMAX
Variant: Amino acid change caused by the variant
PolyPhen2: predicted effect of the variant on the protein function from PolyPhen2
SIFT: predicted effect of the variant on the protein function from SIFT obtained via Variant effect predictor (VEP)
* : Translation stop codon